Over the last month and a half, I've shared several analyses and observations of the CMV ECOcluster: >50,000 TCRs representing humanity's shared, public response to CMV. I seem to be wrapping that up, for now, so I made a new post tying it all together and providing some new tools: https://cmvividly.com/posts/08_practical_tools_tips/

• I implemented a simple TCR repertoire classifier for CMV
• ...and for donor status w.r.t. 12 HLA-A and B alleles (for use in CMV+ repertoires)
• I combined the 2024 and 2026 CMV ECOclusters into a single dataset
• ...and consolidated advice about using it to annotate repertoires from all the earlier posts

This has been a fun little project! I hope it helped some folks make better use of this powerful new resource. If there's anything else you'd like me to take a look at, just log an issue in the CMVividly repo: https://github.com/dhmay/CMVividly/issues/new?template=suggest-an-analysis.md

Damon