Year 2, Week 10
Feb 28-Mar 6, 2026 - time (for) change
Hello friends,
This time last week, I was afraid that writing about open war was overreacting. But since then, more than one thousand people have died, most of them in Iran, including 150 schoolgirls in their classrooms. We think that the school in Minab was destroyed by the US: we know that a ship thousands of miles from the conflict zone was. As the violence expands and the rules of engagement are shredded, it’s hard to disentangle my horror regarding how we got here from my fear about where we’re going.
This newsletter is about science and higher education. Our goal is to stay focused, not flooded. So do we focus on the environmental and human tragedy?1 The imminent energy crisis?2 The potential for economic disaster?3 The answer is yes. It is all connected. We are all connected: the children are always ours.
This was Year 2, Week 10.
What happened in science & higher ed
The administration says it is revoking certification of the union representing some 5,000 early career NIH workers4, on the grounds that they are not technically employees because they are hired on multiyear research grants. This specific argument is new, but the move is part of a large-scale, ongoing attempt to undercut federal employee union protections.5
There’s new polling that contrasts public confidence in career scientists at agencies like NIH, CDC, FDA with lower confidence in those agency’s leadership.6 That distinction matters when we talk about things like FDA progress on drug review. Much of the focus is on how departures and leadership changes are impacting treatment for cancers7 and rare diseases. The agency was in the headlines for its chaos earlier this week. It is not coincidental that news broke today that Vinay Prasad is leaving the FDA (again).8 I find KFF’s analysis very useful here: remember that health policy decisions between now and November are more overtly political than ever, because of the midterms.
For months, I’ve argued that Congressional budget numbers were important, but only the beginning of the battle. Here’s more demonstration of exactly why that is:
We are now 30 days past when the president signed the budget,9 but OMB has not yet authorized NIH to spend its Congressionally-approved budget (beyond salaries).10 It looks like NIH funding is now contingent on earning OMB approval of an unusually detailed spend plan. This delay, on top of the long government shut down, makes it harder for NIH to spend down its budget. If it can’t, that money goes back to the treasury. The latest analysis shows that NIH has made 840 new and competing awards so far this fiscal year: less than a third of what we would expect at this point.
Since January 2025, the NIH has only posted 84 funding opportunities (NOFOs11), compared to more than 750 the year before.12 More than 300 that seem to be pending,13 some of which have been languishing since 2024. There is reasonable a case to be made for fewer, broader NOFOs, but at least one previous NIH director says that NIH institutes will further struggle to spend down their budgets with so few NOFOs.14
And finally, new analysis of the NIH databook reveals a truly shocking dropoff in success for the highest-rated proposals in 2025.15 Just putting your head down and doing excellent work is no protection against this.
And what’s next
This weekend, Stand Up for Science is hosting rallies around the country. It’s hard to believe it’s already been a year since the first one. The next No Kings protests are happening on March 28, and are expected to become the largest mobilization in American history.
Protest is never the only option. This week I’m feeling especially inspired by a volunteer rapid response team of doctors providing at-home care for those who cannot risk getting abducted en route to clinics in Minneapolis. It’s quite different, but I’m really excited about the ‘Science Sunday in the Library’ events we are spinning up this spring in Seattle (more on that soon!). Closer to home, I’m grateful for an upcoming neighbor-to-neighbor teach-in here in Oakland. Wherever we are, whatever capacity we have–we need each other. We’re all connected.
I can’t believe it’s March already, and tomorrow night, Daylight Savings Time begins again.
No time like the present, right? Forward, together.
Liz
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you can get this delivered weeklyLeaders were preparing to evacuate Tehran late last year because of dangerously low water availability. Food is already expensive and people are afraid of shortages. Millions of people are facing the decision to leave their homes in desperate bids for safety and supplies. We are creating catastrophic conditions for refugees across the region. ↩
20% of the global oil and liquid nation gas supply transits through the Strait of Hormuz, which the conflict has effectively closed. Hundreds of tankers are at a standstill now. ↩
Every sector is affected by a war of this scale, in this location. And on top of inflation and shortages we face, experts estimate the initial cost of the war at $900 million per day–$3.7billion in the first 100 hours alone–for the US. ↩
This is the NIH Fellows United-UAW 2750, and they ratified their first contract in 2024. ↩
The IRS just terminated their collective bargaining agreement with the National Treasury Employees Union last week. In August, HHS reversed its recognition of unions representing NIAID and NIH employees, among others, by announcing it to the media first. ↩
TL;DR “Two-thirds of Americans (67%) have confidence in career scientists working at U.S. federal health agencies, compared with just 43% confidence in agency leaders overall.” ↩
The oncology review process managed to approve 16 new cancer drugs in 2025 (a bit above average), despite being at roughly half-power. Thank you all for your service. ↩
It was a big week for firings. The biggest news was that Kristi Noem was removed from her post leading DHS, but you may not have seen that Jeffrey B. Clark is also out. Clark is not a name I knew immediately, but he’s one of the key figures responsible for gutting our climate regulations. He drafted executive orders and worked closely with Vought on developing and executing Project 2025. ↩
Signed on Feb 3, making the 30 day mark March 5, 2026 ↩
Thanks to last year’s change to Circular No. A-11, the OMB’s “Budget Bible.” One of Vought’s other notable changes to the 2025 edition redefines impoundment. ↩
“Notices of Funding Opportunities” ↩
These statements come from Science, and I’m relying on their factcheckers. I always try to doublecheck when we talk about ‘years’ b/c the US federal fiscal year closes at the end of September. So we’re coming to the end of Q2, halfway through. ↩
Official status “forecasted” ↩
One deputy director explains that the reason there are so few NOFOs is that their institute now requires “sixteen steps” to post one. ↩
If your review rank was in the top tenth percentile in any year 2020-2024, your award probability for an R01 or R35 was at or above 95%. If you earned that coveted 10% review rank in 2025? Your chances of getting funding plummeted below 60%. ↩