A short first issue on the practical side of tracking GLP-1 and peptide doses — the arithmetic that trips people up, and the record-keeping that quietly falls apart.

Reconstitution is where most errors start. A vial's strength is not a dose. If you add 2 mL of bacteriostatic water to a 5 mg vial, you have 2.5 mg/mL, so a 0.25 mg dose is 0.1 mL — 10 units on a 100-unit insulin syringe. Change the diluent volume and every number downstream changes with it. Writing down the reconstitution ratio at the moment you mix, rather than reconstructing it later, prevents nearly all of these mistakes.

Titration is a schedule, not a dose. Most GLP-1 protocols step up every four weeks, and the useful record is the step history — what you took, for how long, and what happened — not just the current number. That history is what makes a conversation with a prescriber useful, and what tells you whether a side effect tracked a dose increase or something else entirely.

Logs drift for boring reasons. Injection site rotation gets skipped, a missed dose goes unrecorded, the vial's expiry after first puncture is forgotten. None of these are dramatic on their own; together they make a log untrustworthy after a couple of months.

I keep the calculators and dose history in a free web-based peptide and GLP-1 tracker, which also has plain-language reference pages on semaglutide, tirzepatide, and newer compounds like retatrutide and orforglipron that don't have much readable coverage yet.

Nothing here is medical advice — dosing decisions belong with your prescriber.