🆕 Newsmakers — 1:30p ET, 2026-08-19 — new since last alert

📰 NEW MARKET THEMES: • Trump Says US Has ‘Come to a Deal With Canada' President Donald Trump declared on Wednesday that the US has reached an agreement with Canada on trade, saying that Canadian representatives “gave us the points we had to have.” Trump spoke with Bloomberg's Tyler Kendall at the White House. — youtube.com · 08/19 1:11p https://www.youtube.com/watch?v=HT1g3le7Iys • Goldman's McClure Says IPO Market 'Wide Open' for Business Matthew McClure, Goldman Sachs global co-head of investment, says the IPO market is "open for business," with AI-related companies accounting for more than half of capital raised despite representing about 20% of IPOs this year. Speaking with Dani Burger on "Bloomberg Deals," Mc… — youtube.com · 08/19 1:00p https://www.youtube.com/watch?v=-Yvx9FkP86U • The UAE halts Iran trade; Trump says no talks with Tehran U.S. President Donald Trump reverses course on claims around the status of talks with Iran, saying no negotiations are planned. Elsewhere, the UAE halts trade with Tehran, shortly after reporting two missiles fired in its direction. — youtube.com · 08/19 1:00p https://www.youtube.com/watch?v=qEsv8GLXrc8 • Market Midday: Stocks Higher, Yields Lower on Buyback News, Diesel Surges • 8/19/26 CNBC Business News Update with Jessica Ettinger - Markets & Business News With Expert Analysis From Top Business Names. Visit CNBC.com For More. — youtube.com · 08/19 12:41p https://www.youtube.com/watch?v=rInAxbVEbqw

🐘 NEW BIG-CAP MOVERS:

1. MRNA +148% $156.18 (62B cap) From COVID to Cancer: Moderna Scores Melanoma Breakthrough By successfully applying individualized mRNA technology to train the immune system against recurring tumor cells, Moderna and Merck have opened an extraordinary new frontier in targeted cancer treatment. — zacks.com · 08/19 1:16p https://www.zacks.com/commentary/2977096/from-covid-to-cancer-moderna-scores-melanoma-breakthrough?cid=CS-STOCKNEWSAPI-FT-investment_ideas-2977096

2. HL +12% $20.05 (13B cap) Hecla Mining and Coeur Mining Spike 13% as Treasury Buyback Plan Ignites Precious Metals Rally The bond market is impacting the precious metals space today, it seems. Shares of Hecla Mining (NYSE:HL) are climbing 13% to $20.29 in midday trading Wednesday. — 247wallst.com · 08/19 1:18p https://247wallst.com/investing/2026/08/19/hecla-mining-and-coeur-mining-spike-13-as-treasury-buyback-plan-ignites-precious-metals-rally/

3. CDE +12% $20.64 (21B cap) Hecla Mining and Coeur Mining Spike 13% as Treasury Buyback Plan Ignites Precious Metals Rally The bond market is impacting the precious metals space today, it seems. Shares of Hecla Mining (NYSE:HL) are climbing 13% to $20.29 in midday trading Wednesday. — 247wallst.com · 08/19 1:18p https://247wallst.com/investing/2026/08/19/hecla-mining-and-coeur-mining-spike-13-as-treasury-buyback-plan-ignites-precious-metals-rally/

4. BMNR +11% $20.26 (12B cap) Strategy Rockets 13%, Bitmine Immersion Technologies Rallies 13%, Coinbase Jumps 11% as Bitcoin Surges Past $68,000 Even with the Clarity Act stalled in Congress, the he U.S. Securities and Exchange Commission (SEC) is proposing new cryptocurrency-related rules; this framework is known as “Regulation Crypto Assets. — 247wallst.com · 08/19 12:38p https://247wallst.com/investing/2026/08/19/strategy-rockets-13-bitmine-immersion-technologies-rallies-13-coinbase-jumps-11-as-bitcoin-surges-past-68000/

5. PFE +3% $28.16 (160B cap) Pfizer's Obesity Push: Can Berobenatide Take Market Share? PFE aims to break into the obesity market with berobenatide, a potential monthly treatment designed to compete with leading GLP-1 therapies. — zacks.com · 08/19 12:46p https://www.zacks.com/stock/news/2977069/pfizer-s-obesity-push-can-berobenatide-take-market-share?cid=CS-STOCKNEWSAPI-FT-analyst_blog|quick_take-2977069

📈 NEW GAINERS:

1. MRNA +148% $156.41 (62B cap) From COVID to Cancer: Moderna Scores Melanoma Breakthrough By successfully applying individualized mRNA technology to train the immune system against recurring tumor cells, Moderna and Merck have opened an extraordinary new frontier in targeted cancer treatment. — zacks.com · 08/19 1:16p https://www.zacks.com/commentary/2977096/from-covid-to-cancer-moderna-scores-melanoma-breakthrough?cid=CS-STOCKNEWSAPI-FT-investment_ideas-2977096

2. BNTX +20% $111.09 (28B cap) Why Is BioNTech Stock Surging on Wednesday? BioNTech SE (NASDAQ:BNTX) stock is trading higher on Wednesday. Investors are probably reacting to Merck & Co Inc. (NYSE:MRK) and Moderna, Inc. (NASDAQ:MRNA) topline data from individualized cancer therapy for advanced skin cancer. — benzinga.com · 08/19 12:39p https://www.benzinga.com/trading-ideas/movers/26/08/61308634/why-is-biontech-stock-surging-on-wednesday

3. EL +17% $98.53 (36B cap) Estee Lauder Q4 Earnings Beat Estimates, Sales Up 6% Y/Y EL beats fiscal fourth-quarter estimates as sales rise 6%, fueled by Skin Care and Fragrance growth and sharply higher operating income. — zacks.com · 08/19 1:06p https://www.zacks.com/stock/news/2977097/estee-lauder-q4-earnings-beat-estimates-sales-up-6-y-y?cid=CS-STOCKNEWSAPI-FT-analyst_blog|earnings_article-2977097

— new items only (already-sent headlines filtered). Full list in the 10am/3pm digest.