Hacker News Top Stories with Summaries (January 19, 2024)
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<h1> Hacker News Top Stories</h1>
<p>Here are the top stories from Hacker News with summaries for January 19, 2024 :</p>
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We migrated our PostgreSQL database with 11 seconds downtime
Summary: The Government Digital Service (GDS) successfully migrated its PostgreSQL database to Amazon Web Services (AWS) with only 11 seconds of downtime. The process involved using AWS Database Migration Service (DMS) to transfer data from the source to the target database while minimizing disruption. The GDS team followed a multi-stage migration process, including setting up the DMS instance, creating the target database, and managing traffic during the migration. The result was a smooth transition with minimal downtime for users.
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AlphaFold Found Possible Psychedelics
Summary: Researchers have used DeepMind's AlphaFold to identify hundreds of thousands of potential new psychedelic molecules for antidepressant development. This marks the first time AlphaFold predictions have been shown to be as useful for drug discovery as experimentally derived protein structures. The findings could boost the AI tool's application in the pharmaceutical industry and expedite drug discovery projects by years.